| ncRNA name | CD9 siRNA |
| ncRNA Category | siRNA |
| Disease name | choroidal neovascularization (CNV) |
| Species | Mus musculus |
| Tissues/Cell_line | flat mounts |
| Methods | siRNA injection, fluorescence microscope |
| Expression pattern | associated |
| Functional description | Injecting CD9-specific small interfering RNA (siRNA-CD9) markedly inhibited HGF- or VEGF-induced subconjunctival angiogenesis in vivo. Furthermore, intravitreous injections of siRNA-CD9 or anti-CD9 antibodies were therapeutically effective for laser-induced retinal and choroidal neovascularization in mice, a representative ocular angiogenic disease model. |
| PubMed ID | 21875571 |
| Year | 2011 |
| Title | Targeting CD9 produces stimulus-independent antiangiogenic effects predominantly in activated endothelial cells during angiogenesis: a novel antiangiogenic therapy. |
| Drug-related ncRNA | NO |
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